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Editor's Correspondence |

Thrombolytic Therapy for Pulmonary Embolism

James E. Dalen, MD, MPH
Arch Intern Med. 1998;158(15):1716. doi:.
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I agree that if thrombolytic therapy resolves pulmonary embolic obstruction more rapidly than heparin, it would decrease the probability that an early recurrent embolus would result in hemodynamic compromise or death. Concern for the impact of early recurrent pulmonary embolism is one of the reasons that some investigators recommend inferior vena cava interruption in patients with massive pulmonary embolism.

With regard to mobile right ventricular thrombus, I agree that there is some evidence to suggest that patients with this disease might benefit from the use of thrombolytic therapy.

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