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Comment & Response |

Exercise, Cardiac Rehabilitation, and Post–Acute Coronary Syndrome Depression—Reply

Karina W. Davidson, PhD1; Matthew M. Burg, PhD1,2; Robert M. Carney, PhD3; Kenneth E. Freedland, PhD3
[+] Author Affiliations
1Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, New York
2Yale University School of Medicine, New Haven, Connecticut
3Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri
JAMA Intern Med. 2014;174(1):166-167. doi:10.1001/jamainternmed.2013.11097.
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In Reply We thank Lavie and colleagues for their interest in the results of our recently published Comparison of Depression Interventions After Acute Coronary Syndrome (CODIACS) Vanguard trial,1 which showed that depressed patients with acute coronary syndrome (ACS) randomized to centralized, stepped, patient-preference depression treatment (psychotherapy or medication use) had substantially fewer depressive symptoms after 6 months compared with those receiving enhanced usual care. We also demonstrated that we could deliver this depression treatment by telephone and/or by webcast across a number of different health care settings in geographically diverse areas. These elements will be vital design components of a future phase 3 trial of depression treatment for patients with ACS.

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January 1, 2014
Carl J. Lavie, MD; Richard V. Milani, MD; James A. Blumenthal, PhD
1Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School–The University of Queensland School of Medicine, New Orleans, Louisiana2Department of Preventive Medicine, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge
1Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School–The University of Queensland School of Medicine, New Orleans, Louisiana
3Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina
JAMA Intern Med. 2014;174(1):165-166. doi:10.1001/jamainternmed.2013.11112.
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