Accepted for Publication: March 13, 2013.
Published Online: June 17, 2013. doi:10.1001/jamainternmed.2013.6633.
Study concept and design: Pan, Manson, Willett, Hu.
Acquisition of data: Pan, Sun, Manson, Willett, Hu.
Analysis and interpretation of data: All authors.
Drafting of the manuscript: Pan.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Pan, Sun, Bernstein, Willett.
Obtained funding: Willett and Hu.
Administrative, technical, or material support: Manson, Hu.
Study supervision: Manson, Willett, Hu.
Conflict of Interest Disclosures: None reported.
Funding/Support: The study was supported by grants P01CA087969, R01CA050385, U19CA055075, R01DK058845, P30DK046200, and U54CA155626 from the National Institutes of Health. Dr Sun was supported by career development award K99HL098459 from the National Heart, Lung and Blood Institute.
Role of the Sponsors: None of the funding sponsors was involved in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.
Additional Contributions: We thank participants in the Health Professionals Follow-up Study, Nurses’ Health Study, and Nurses’ Health Study II for their continuing outstanding support and the colleagues working on these studies for their valuable help.