This case series explores the safety considerations of clarithromycin by investigating the association between Helicobacter pylori therapy containing clarithromycin and acute neuropsychiatric events.
This Teachable Moment highlights the risk of polypharmacy in the treatment of neuropsychiatric symptoms, the complexity of prognostication in dementia, and the importance of a multifaceted approach to neuropsychiatric symptoms.
This cohort study uses The Health Improvement Network data to assess whether statin users show acute decline in memory compared with nonusers and compared with users of nonstatin lipid-lowering drugs.
This randomized clinical trial found that a Mediterranean diet supplemented with olive oil or nuts is associated with improved cognitive function in older people.
This cohort study finds that low daytime systolic blood pressure was independently associated with a greater progression of cognitive decline in older patients with dementia and mild cognitive impairment among those treated with antihypertensive drugs. See the Invited Commentary by Sabayan and Westendorp.
To evaluate the association between hypoglycemia and dementia, Yaffe et al studied 783 older adults with diabetes mellitus who were participating in the prospective population-based Health ABC Study beginning in 1997. Dementia diagnosis and hypoglycemic events were determined during the follow-up period. See the Invited Commentary by Lipska and Montori.