This study of data pooled from 5 mammography registries found that computer-aided detection (CAD) does not improve diagnostic accuracy of mammography, and these results suggest that insurers pay more for CAD with no established benefit to women.
Results of this secondary analysis of the PREDIMED trial suggest a beneficial effect of a Mediterranean diet supplemented with extra-virgin olive oil in the primary prevention of breast cancer.
Johansen Taber and coauthors discuss the need for rigorous studies to assess the utility of whole-genome and whole-exome sequencing in large groups of patients, including comparative studies with other approaches to screening and diagnosis, and the evaluation of clinical end points and health care costs. Although whole-genome or whole-exome sequencing show great promise, they should be incorporated into patient care only in limited clinical situations.
This study examines low-value health care spending among US adults ages 18 to 64 years using data from Optum Clinformatics Datamart of UnitedHealthcare commercial claims for 2011 to 2013.
Schiff and coauthors study patterns of primary care malpractice types, causes, and outcomes as part of a Massachusetts ambulatory malpractice risk and safety improvement project. See Invited Commentary by Hyman and Sage.
This population-based study evaluates the effect of the Medicare Pioneer accountable care organization program on the use of what are considered to be low-value services.
This systematic review summarizes the available published evidence on associations between patient survival and surrogate end points used in medical oncology trials and find the correlations to be generally low.