This cross-sectional survey study measures changes in outpatient quality and patient experience in the United States from 2002 to 2013 to determine whether efforts to improve outpatient quality have been successful.
This cohort study reports on the association of receipt of antibiotics by prior hospital bed occupants with increased risk for Clostridium difficile infection in patients subsequently occupying the same bed.
This analysis uses proprietary administrative data to estimate patterns of inpatient antibiotic usage in the United States from January 1, 2006, to December 31, 2012.
This randomized clinical trial examines whether azithromycin added to standard care for asthma attacks in adults results in clinical benefit.
This noninferiority trial compares the effects of IDSA/ATS guideline–recommended vs conventional antibiotic treatment duration on symptom and clinical resolution in hospitalized patients with community-acquired pneumonia.
This audit of virtual visits for urgent health care uses standardized patients to assess the variation in quality among 8 companies that offer virtual visits.
Baseline, new acquisition, and duration of hand carriage of multidrug-resistant organisms among patients newly admitted to post–acute care facilities from acute care hospitals is evaluated.
This case report uses the example of an older woman with paronychia to discuss judicious use of antibiotics for skin conditions in the outpatient setting.
This trial of patients with uncomplicated respiratory infections randomizes participants to 1 of 4 antibiotic prescription strategies to determine whether delayed antibiotic strategies are associated with greater symptom burden and duration, as well as reduced antibiotic use.
This population-level analysis of early trends in use of the services targeted by the Choosing Wisely campaign showed both desirable and undesirable modest changes in use of low-value services, suggesting that additional interventions are necessary for wider implementation of the recommendations.
This case illustrates how unnecessary antibiotic use might cause life-threatening adverse events in the context of certain types of heart disease.
This cohort study of hospitalized adults with suspected Clostridium difficile infection compared complications and deaths among those with positive vs negative polymerase chain reaction and toxin immunoassay test results.
This nested case-control analysis of database records found that use of fluoroquinolones was associated with an increased risk of aortic aneurysm and dissection.
This cohort study of appropriate orders for urinalysis determines whether overuse of urinalysis contributes to misdiagnosis and excessive use of antibiotics among elderly patients admitted to the emergency department of a tertiary care center.
This longitudinal open-cohort study of antibiotic use in nursing home residents found that residents of high-use homes are exposed to an increased risk of antibiotic-related harms even if they have not directly received antibiotics.