This randomized clinical trial investigates participation rate, adenoma yield, performance, and adverse events of population-based colonoscopy screening in several European countries.
This commentary on a recently published article from the JAMA Network places in context findings on risks of malfunction in cardiovascular implantable electronic devices during radiation therapy for cancer.
This study investigates patient and event characteristics associated with manufacturers’ delayed submission of expedited adverse event reports to the US Food and Drug Administration.
This computerized bibliographic search assesses the efficacy and safety of the sublingual tablets licensed as drugs in the treatment of patients with seasonal allergic rhinoconjunctivitis to grass pollen.
This systematic review assessed the quality of interdisciplinary team care interventions in general medical patients, and evidence suggests that these interventions have little effect on traditional measures of health care quality.
This systematic review assessed the safety and procedural success of the Lariat device, and the investigators found significant risks of major adverse events with off-label use for left atrial appendage exclusion.
This blinded data review of a prospectively collected database of adult patients admitted or observed with potentially ischemic chest pain found that the risk for a clinically relevant adverse cardiac event was rare and commonly iatrogenic.
This retrospective study of an academic health care system that used nondisclosure clauses in most malpractice settlement agreements found that the causes were often broader than necessary.
This randomized clinical trial found that 1 dose of zoledronic acid improved bone mineral density over 2 years in frail elderly women with osteoporosis, but the clinical importance of nonsignificant increases in fracture and mortality needs further study.
This systematic review of English-language articles published in 2013 shows that both clinical trials and observational studies highlighted frequently overused or unnecessary care.
Andersson et al assess the association of β-blocker treatment with major cardiovascular adverse events and all-cause mortality in patients with ischemic heart disease undergoing noncardiac surgery. Also see the invited commentary by Whelton and Bansal.